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Viagra is a very effective drug in combating impotence Sildenafil Citrate Erectile dysfunction and its causes What does impotence mean? What are the main causes of Impotence?

Sildenafil Citrate

With the advent of industrialization, impotence is deepening its claws in the community especially effecting older men. Men who have been stabbed with the dagger of impotence suffer from the shameful condition of being unable to erect their penis. Humiliating penile flaccidity takes the place of potent erection in those bearing impotence. Emotional disturbances and nutritional deficiencies are the major risk factors precipitating impotence. Pfizer pharmaceuticals, a highly successful pharmaceutical company, is on the way of searching new horizons in the sky of the world of drug industry. Pfizer has come up with the ultimate most promising solution to the curse of impotence by developing a highly effective drug Viagra. Pfizer’s Viagra is fighting impotence successfully since 1998. Viagra is now the doctors first choice and the most efficient drug available for impotence in the market.

Erection is a complicated process which starts when you receive any sexual stimulation like watching an erotic scene or sexual touch of your spouse. The brain responds to this stimulation by sending signals to the blood vessels of penis. Endothelial cells present in the walls of the blood vessels of the penis, under the influence of signals from brain, synthesize and release Nitric Oxide into the lumen of penile vessels. In the vessels, Nitric Oxide causes activation of guanylyl cyclase which is an enzyme responsible for production of cGMP from GTP. cGMP bears the pivotal role in erection performing the job of dilating the vessels. Dilation of blood vessels results in flooding of blood into the spongy tissue-carpus cavarnose of the penis hence causing erection. Impotence is because of decreased level of cGMP. Viagra increases the quantity of cGMP in the blood vessels of the penis by demolishing the action of phosphodiesterase which is an enzyme responsible for conversion of cGMP into GMP. However there will be no erection if the drug action is not supplemented with sexual stimulation.

Used all over the world by every happy couple in accelerating their sexual drive and in feeling the ever dreamt sexual climax, Viagra boasts of its efficacy within safety and health friendly interaction in the body of the user. Its generic name, Sildenafil Citrate, comes in the name of Viagra in three drug dosage forms, 25 mg, 50 mg and 100 mg tablets. The drug is strictly contraindicated with nitrate containing drugs, erythromycin, protease inhibitors, hepatic diseases, renal problems and heart failure or myocardial infarction not to mention a cerebral stroke. Possible side effects of the drug include dizziness, cyanotic vision, hearing impairment, diarrhea, runny nose, stuffy nose, hypotension, priapism, headache and flushing. In case of persistence of any of the side effects, seek medical assistance immediately. Do not take the drug more than once a day or life threatening hypotension might take place. Avoid consuming alcohol while interacting sexually as it might interfere with drug metabolism.

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